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Efficacy of Tele-CPASS Compared to In-person CPASS Therapy for Upper Extremity Motor Recovery

RecruitingNAAges 21 Years - anyAllUniversity of Texas, El Paso
NCT07661849 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study evaluates whether a home-based telerehabilitation program (tele-CPASS) is as effective as an in-person rehabilitation program (CPASS) for improving arm and hand function after stroke. Stroke often leads to long-term difficulty using the affected arm in daily activities, and access to in-person therapy can be limited. This study aims to determine whether therapy delivered remotely can provide similar benefits to standard in-clinic care. Participants who recently experienced a stroke will be randomly assigned to receive 20 hours of upper extremity rehabilitation therapy either in person or through a telehealth platform. Both groups will receive the same type and amount of therapy focused on practicing meaningful, patient-selected daily activities. Participants will complete assessments before treatment, immediately after treatment, and at 6 and 12 months to measure recovery of

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 21 years or older * Neuroimaging-confirmed stroke within 40 days prior to enrollment * Persistent hemiparesis resulting in impaired upper extremity function, defined by a score of 0 to 3 on the NIH Stroke Scale motor arm item * Able to participate in all study-related activities, including 1-year follow-up * Short Blessed Memory Orientation and Concentration Scale score less than 8 * Able to follow 2-step commands * Montreal Cognitive Assessment (MoCA) score greater than 25 * No upper extremity injury or condition that limited upper extremity use prior to the stroke Exclusion Criteria: * Inability to provide informed consent * Persistent disabling neurologic condition, such as multiple sclerosis, Parkinsonism, amyotrophic lateral sclerosis, or dementia requiring medication * Clinically significant fluctuations in mental status within 72 hours prior to randomization * Active psychosis, psychosis within the prior 2 years, active substance abuse, or prior substance abuse * Dense sensory loss, defined by a score of 3 or 4 on the NIH Stroke Scale sensory item * Ataxia out of proportion to weakness in the affected arm, defined by a score greater than 1 on the NIH Stroke Scale ataxia item * Not expected to survive 12 months because of other illnesses * Pregnancy * Severe aphasia * Receipt of botulinum toxin or expectation of receiving botulinum toxin during the study period
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What it tests

  • Tele-CPASS
  • In-person CPASS therapy
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Where

3 sites
Rehabilitation Sciences Complex, University of Texas at El Paso, 3333 N Mesa St, El Paso, TX 79902
El Paso, United States
Texas Tech University Health Sciences Center El Paso - Neurology Clinic
El Paso, United States
University Medical Center of El Paso - Rehabilitation Services
El Paso, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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