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Development of a Pharmacogenomic Panel for Early Detection of Chemotherapy- and Immunotherapy-Induced Cardiotoxicity.

Recruitingn/aAges 18 Years - anyAllBeneficência Portuguesa de São Paulo
NCT07663357 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To evaluate the use of a pharmacogenetic and pharmacoepigenetic panel for predicting chemotherapy- and immunotherapy-induced cardiotoxicity in cancer patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with a confirmed diagnosis of breast cancer who are scheduled to initiate treatment with anthracyclines and/or HER2-targeted therapies (anti-HER2 therapies). Exclusion Criteria: * Patients with a left ventricular ejection fraction (LVEF) \< 50%; * Patients who have undergone chemotherapy and/or radiotherapy within the previous year; * Patients with chronic kidney disease and a glomerular filtration rate (GFR) \< 30 mL/min/1.73 m²; * Patients with uncontrolled hypertension; * Patients with complex congenital heart disease.
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What it tests

  • Not listed
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Where

6 sites
Instituto do Câncer do Ceará
Fortaleza, Brazil
Complexo Hospitar HUOC/PROCAPE
Recife, Brazil
Universidade Federal de Santa Catarina
Florianópolis, Brazil
Hospital Beneficente UNIMAR
Marília, Brazil
FAMERP - Faculdade de Medicina de São José do Rio Preto
São José do Rio Preto, Brazil
Hospital BP - A Beneficência Portuguesa de São Paulo
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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