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Targeting Sedentary Behavior Reduction and Physical Fitness Enhancement in Women Before and Beyond Bariatric Surgery- BARIMOV Study Protocol

RecruitingNAAges 18 Years - anyFemaleHospital de Sao Sebastiao
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In plain words

What the trial is, and whether it could suit you

Introduction: Sedentary behavior (SB) and insufficient physical activity (PA) interact to worsen physical fitness (PF), obesity-related complications and diseases (ORCD), and all-cause mortality in women with obesity. Replacing SB with low-intensity PA may improve PF and ameliorate ORCD, with potential lasting effects after bariatric surgery (BS). However, strong evidence on how PF influences BS outcomes and whether preoperative PA interventions can improve postoperative outcomes is lacking. The BARIMOV study aims to evaluate the effects of a structured sedentary behavior reduction program (SBRPro) on PF, investigate whether PF improvements influence BS outcomes, and explore potential mechanistic pathways by characterizing molecular adaptations in peripheral blood, skeletal muscle, and visceral adipose tissue (VAT). Methods: BARIMOV is a prospective cohort study with five assessment tim

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult women (≥ 18 years); * BMI of 30-45 kg/m2; * Scheduled for primary vertical sleeve gastrectomy or Roux-en-Y gastric bypass; * Capacity to provide informed consent, adequate proficiency in the national language; * Access to the internet and mobile phone communication. Exclusion Criteria: * Previous bariatric surgery or gastric surgical procedure; * Physical incapacity or medical contraindications precluding physical fitness testing or participation (active cardiac disease, uncontrolled hypertension, severe joint disease); * Pregnancy or breastfeeding; * Inability to provide informed consent or comply with study procedures; * Patients with type 1 or 2 diabetes mellitus.
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What it tests

  • Sedentary behavior reduction program on physical fitness.
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Where

1 site
Unidade Local de Saúde de Entre Douro e Vouga
Santa Maria da Feira, Portugal
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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