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Comparison of Digital Analysis and Artificial Intelligence for Cephalometric Tracing

Recruitingn/aAges any - anyAllUniversity of Pavia
NCT07664488 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the accuracy and reliability of artificial intelligence (AI)-based cephalometric analysis compared with digital manual tracing. A total of 100 standardized lateral cephalometric radiographs will be analyzed using Delta-Dent software with manual landmark identification and three fully automated AI-based systems (WebCeph, QuantX, and Smartee). Sagittal, vertical, dental, and soft tissue cephalometric parameters will be compared among the different methods. Statistical analysis will assess inter-method agreement and the clinical relevance of any observed discrepancies. The study seeks to determine whether AI-based systems provide measurements comparable to conventional digital tracing and whether they can be considered reliable adjunctive tools in orthodontic diagnosis and treatment planning.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Availability of digital lateral cephalometric radiographs of adequate diagnostic quality * Radiographs acquired with patients in centric occlusion and proper head positioning using a cephalostat * Patients of any age and sex * Absence of congenital or acquired craniofacial anomalies * No previous orthodontic treatment * No previous orthognathic surgical treatment * Absence of agenesis of incisors or first molars * Absence of supernumerary teeth overlapping the region of interest Exclusion Criteria: * Radiographs presenting artifacts or inadequate visualization of anatomical structures * History of significant craniofacial trauma * Radiographs acquired without a cephalostat * Presence of severe skeletal asymmetries * Incomplete clinical or radiographic records * Radiographs unsuitable for manual or AI-based cephalometric landmark identification
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What it tests

  • Cephalometric Analysis
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Where

1 site
Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia, Pavia, Lombardy 27100
Pavia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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