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Beetroot Extract and Quality of Life in Adults Aged 75 and Over

RecruitingNAAges 75 Years - anyAllFundacion Miguel Servet
NCT07666685 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The increasing number of adults aged 75 years and older highlights the need for effective, low-cost interventions to preserve cardiovascular health, functional independence, and cognitive performance and to support healthy aging. Beetroot extract (BE), derived from "Beta vulgaris", contains high levels of inorganic nitrate and other bioactive compounds that may positively influence vascular and neuromuscular function. In parallel, multicomponent physical exercise is recognized as an effective strategy to improve physical and cognitive outcomes in older adults. However, evidence on the independent and combined effects of BE supplementation and structured exercise in very old adults remains limited. This randomized controlled trial is designed to evaluate the effects of BE supplementation, alone and in combination with a multicomponent physical exercise program, on blood pressure, functio

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Adults aged 75 years and older recruited from the Geriatrics Service of the Hospital Universitario de Navarra (HUN) or primary care settings. 2. Ability to ambulate independently. 3. Ability to communicate effectively. 4. Ability to tolerate physical exercise. 5. Barthel Index score greater than 60 points. Exclusion Criteria: 1. Refusal or inability of the participant, caregiver, or legal guardian to provide written informed consent. 2. Advanced or severe dementia (Global Deterioration Scale \[GDS\] stages 6-7). 3. Unstable medical condition or terminal illness with a life expectancy of less than 6 months. 4. Ischemic heart disease or congestive heart failure. 5. Severe renal insufficiency. 6. Hypotension.
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What it tests

  • Beetroot Extract Supplementation
  • Placebo group: nitrate-depleted beetroot juice
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Where

1 site
Hospital Universitario de Navarra
Pamplona, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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