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Neuropathic Dental Pain & DBS

RecruitingNAAges 19 Years - 80 YearsAllUniversity of British Columbia
NCT07671950 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational study will evaluate pain outcomes in patients with neuropathic dental pain (Atypical Odontalgia/Phantom Tooth Pain) who undergo directional deep brain stimulation (DBS). Participants will complete validated pain, disability, quality-of-life, and mood assessments before surgery and following DBS programming. Directional stimulation will be applied to different thalamic targets to determine whether specific stimulation settings are associated with greater pain relief. The study aims to characterize changes in pain and quality of life following DBS and to identify the stimulation target associated with the greatest reduction in neuropathic dental pain.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 19 to 80 years. * Diagnosis of Atypical Odontalgia (AO) (also known as neuropathic dental pain). * Receiving deep brain stimulation (DBS) treatment for AO due to inadequate response to conventional therapies, including: Pharmacological therapies, and/or Local anesthetics, corticosteroid injections, or nerve blocks. * Able and willing to provide informed consent. Exclusion Criteria: * Refusal or inability to provide informed consent. * Known major depression. * Acute psychosis.
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What it tests

  • Directional Deep Brain Stimulation
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Where

1 site
Vancouver General Hospital
Vancouver, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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