๐ŸŒ EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis

RecruitingNAAges 30 Years - 50 YearsAllAl-Azhar University
NCT07673185 on ClinicalTrials.gov โ†—
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This randomized double-blind placebo-controlled clinical trial aims to evaluate the clinical and biochemical effects of omega-3 fatty acids combined with low-dose aspirin as an adjunct to scaling and root planing (SRP) in smoker patients with Stage III periodontitis. The study compares test and control groups regarding periodontal clinical parameters and gingival crevicular fluid interleukin-1 beta (IL-1ฮฒ) levels Or other inflammatory markers that will be determined later at baseline, 3 months, and 6 months following treatment

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * \- Male or female smokers aged 30 to 50 years. * Diagnosed with Stage III periodontitis according to the 2017 World Workshop classification. * Probing pocket depth (PPD) โ‰ฅ 5 mm. * Clinical attachment loss (CAL) โ‰ฅ 5 mm. * Presence of at least 20 natural teeth. * Willing and able to provide written informed consent. Exclusion Criteria: * \- Systemic diseases affecting periodontal health. * Pregnancy or lactation. * Periodontal treatment within the previous 6 months. * Use of antibiotics or anti-inflammatory drugs within the previous 6 months. * Allergy or hypersensitivity to omega-3 fatty acids or aspirin. * Long-term anticoagulant therapy. * History of gastric ulcer or bleeding disorders. * Participation in another clinical trial within the previous 3 month
๐Ÿ’Š

What it tests

  • Omega-3 Fatty Acids (EPA plus DHA) plus low dose aspirin
  • Placebo
๐Ÿ“

Where

1 site
Faculty of Dental Medicine for Girls, Al-Azhar University
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy