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Duodenal-jejunal Bypass Sleeve (DJBS) for Obesity and Metabolic Syndrome

RecruitingNAAges 18 Years - 65 YearsAllChinese University of Hong Kong
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In plain words

What the trial is, and whether it could suit you

This study is designed to evaluate the efficacy, safety, and mechanisms of duodenal-jejunal bypass sleeve in patients with obesity

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Body mass index (BMI) ≥27.5kg/m2; or BMI ≥25 kg/m2 with metabolic syndrome Exclusion Criteria: * Patients who have lost more than 5 kg of weight in the past three months * Patients who have used glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the past three months * Patients who are currently taking weight loss drugs such as orlistat * Those who have taken antiplatelet drugs or anticoagulant drugs such as aspirin in the past month * iron deficiency or iron deficiency anemia * Gastrointestinal malformations, such as patients with gastrointestinal atresia or other patients who will cause gastrointestinal implantation failure * Those with a history of cholecystitis and liver abscess * There is a known infection, and the type of disease and the severity of the infection are not suitable for use by clinicians * coagulation dysfunction; * Severe liver and kidney dysfunction, AST /ALT \> 2.5 times, total bilirubin \> 35 μmol/L, blood creatinine concentration greater than 180 μmol/L * Patients with ASA IV \& V * Drug or alcohol abuse addiction or suffering from uncontrollable mental illness * Duodenal bulb ulcer, gastric ulcer or previous and existing pancreatitis * Coronary heart disease, angina, cardiac function grade III or above, or pulmonary dysfunction * Patients who have undergone ERCP before * Patients with potential bleeding or telangiectasia in the stomach, esophagus, small intestine and other parts * Have a history of systemic lupus erythematosus, scleroderma * Those who have contraindications to endoscopy (judged by clinicians) * Pregnant women or those who are preparing to become pregnant * Those who are allergic to nickel-titanium * Any other situation that the clinician deems unsuitable for participation in this product
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What it tests

  • Implantation of duodenal-jejunal bypass sleeve
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Where

2 sites
Chinese University of Hong Kong
Shatin, Hong Kong
CUHK Medical Centre
Shatin, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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