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Observational, Non-interventional Biomarker and Endotyping Study

Recruitingn/aAges 18 Years - anyAllPrenosis, Inc.
NCT07675265 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to establish a centralized ARDS biorepository of longitudinal biospecimens and harmonized clinical data, develop unsupervised, therapy-agnostic endotyping algorithms, and develop unsupervised, therapy-specific treatment-prediction algorithms over a 24 month period.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * ARDS Diagnosis (New Global Definition of ARDS) * Timing: Acute onset within 7 days * Radiology: Bilateral pulmonary opacities * Hypoxia: Non-intubated ARDS: PaO2:FIO2\<300mmHg or SpO2:FIO2\<315 (if SpO2\<97%) on HFNO with flow of \>30 L/min or NIV/CPAP with at least 5 cm H2O end-expiratory pressure; or Intubated ARDS: PaO2:FIO2\<300 mm Hg or SpO2:FIO2\<315 (if SpO2\<97%) * ICU admission * Enrolled within 72 hours of meeting inclusion criteria Exclusion Criteria: • Primary cardiogenic pulmonary edema
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What it tests

  • Not listed
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Where

1 site
Carle Foundation Hospital
Urbana, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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