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Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction.

RecruitingNAAges 18 Years - anyMaleCentre of Postgraduate Medical Education
NCT07676942 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The development of chronic postoperative pain (CPP) following surgery is influenced by several factors, among which the intensity of acute postoperative pain in the immediate perioperative period and mechanisms related to nerve fiber injury play a crucial role. Previous studies have demonstrated that factors such as the severity of early postoperative pain, patient age, and the extent of surgical intervention may increase the risk of transition from acute to chronic pain. In recent years, growing attention has been directed toward anesthetic techniques and adjuvant analgesics (co-analgesics) administered during surgery, which may potentially reduce the incidence of CPP. The aim of this study is to evaluate the effects of intraoperative intravenous infusions of dexmedetomidine or lidocaine during urethral reconstructive surgery on postoperative pain intensity, patient-reported quality of

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📋 Eligibility rules (as published)
Inclusion Criteria: * ASA status less or equal 3 * Scheduled for reconstructive surgery of urethra * Able to understand information provided and to sign informed consent for participation in the study Exclusion Criteria: * known allergy to one of the investigated medications * current chronic pain * known chronic use of opioids, gabapentinoids and antidepressants
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What it tests

  • Perioperative lidocaine infusion
  • Perioperative dexmedetomidine infusion
  • Perioperative placebo infusion
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Where

1 site
Department of Anesthesiology and Intensive Care, Centre of Postgraduate Medical Education
Warsaw, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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