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The Effect of Bottle PEP Exercise on Expiratory Muscle Thickness, Strength, and Balance Parameters in Parkinson's Disease Patients

Recruitingn/aAges 18 Years - 75 YearsAllMarmara University
NCT07680725 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by rigidity, tremor, postural instability, bradykinesia, and autonomic dysfunction. It is a common movement disorder worldwide. Motor impairments in PD patients are not limited to the muscles of the extremities; the neck, upper respiratory tract, and respiratory muscles are also affected. The resulting pulmonary dysfunction is one of the main factors contributing to morbidity and mortality in PD patients. Respiratory muscle exercise programs have been used to improve lung and swallowing function in patients with Parkinson's disease and other similar neurodegenerative disorders. Studies of inspiratory muscle exercise in Parkinson's patients have reported improvements in inspiratory muscle strength and endurance. Similarly, expiratory muscle exercise protocols have been shown to increase maximum expiratory

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with a confirmed Parkinson's diagnosis who are being monitored * Those aged 18-75 * Patients who are ambulatory Exclusion Criteria: * Patients with acquired primary motor neuron disease (ischemic/hemorrhagic stroke, intracranial mass) and additional neurological diagnoses * Patients with hearing and cognitive impairments that prevent them from understanding or performing the exercise program * Presence of concomitant acute or chronic lung disease * History of thoracic or abdominal surgery * Severe heart disease * Active cancer * Mini-Mental State Examination (MMSE) score ≤ 24 * Active smoking
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What it tests

  • Not listed
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Where

1 site
Marmara University Medical Faculty
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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