🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Noninvasive Brain Stimulation for Cervical Dystonia

RecruitingNAAges 18 Years - 85 YearsAllFondazione Policlinico Universitario Campus Bio-M…
NCT07681284 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The primary aim of this study is to assess whether continuous theta-burst stimulation (cTBS) can be helpful in reducing symptoms of idiopathic cervical dystonia. This will be a parallel-group, randomised, sham-controlled, double blind clinical trial. Patients and investigators measuring patient symptoms clinical scales will be blinded from allocation group, investigators delivering the intervention will not be blinded, as this is not feasible. Real cTBS will be compared to sham cTBS, with patients allocated to these two groups with a 1:1 recruitment ratio. Bilateral cTBS will be delivered four times daily, over eight days, for a total of 32 bilateral cTBS sessions. The primary outcome is the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). This will be administered at T1 (pre-cTBS), T2 (day 10, following days 2-9 where patients received the intervention), T3 (2 weeks post th

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria * Aged between 18 and 85 years * Diagnosis of idiopathic cervical dystonia made by an expert physician * Last botulinum toxin injection administered at least two months before the start of participation in the study (Albanese, Abbruzzese et al. 2015) Exclusion Criteria * Head or neck trauma occurring less than 12 months before the onset of dystonia * Acquired dystonia (e.g., drug-induced, brain lesions or trauma) * History of major psychiatric disorders (e.g., bipolar disorder, schizophrenia, obsessive-compulsive disorder) * History of neurological diseases other than CD (e.g., epilepsy, Parkinson's disease) * Other contraindications for TMS or brain MRI (e.g., metal in the head) * Pregnant or breastfeeding women * History of substance abuse or dependence
💊

What it tests

  • Active continuous theta-burst stimulation
  • Sham continuous theta-burst stimulation
📍

Where

1 site
Università Campus Bio-Medico
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy