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Betamethasone vs Dextrose Injections in Trigger Finger

RecruitingNAAges 18 Years - 75 YearsAllIstanbul University - Cerrahpasa
NCT07681804 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in patients with trigger finger. Trigger finger is a common hand condition characterized by pain, clicking, and locking of the finger due to tendon entrapment at the A1 pulley. Corticosteroid injections are widely used as a first-line treatment; however, they may be associated with potential side effects. Dextrose injection is an alternative treatment that may promote tissue healing through regenerative mechanisms. However, there is limited high-quality evidence regarding its effectiveness in trigger finger. In this randomized controlled trial, patients will be assigned to receive either betamethasone or dextrose injection under ultrasound guidance. The primary outcome will be pain intensity measured by the Numeric Rating Scale (NRS). Secondary outcomes will include triggering sever

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 75 years * Clinical diagnosis of trigger finger * Presence of symptoms for at least 4 weeks Exclusion Criteria: * Previous surgery on the affected finger * Injection treatment to the affected finger within the previous 3 months * Active local or systemic infection * Active malignancy * Active inflammatory rheumatic disease (e.g., rheumatoid arthritis, ankylosing spondylitis, polymyalgia rheumatica, vasculitis) * Uncontrolled diabetes mellitus and/or uncontrolled hypertension * Autoimmune connective tissue diseases (e.g., systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis, Sjögren syndrome, polymyositis, dermatomyositis, adult-onset Still's disease) * Coagulopathy that increases the risk of injection procedures * Pregnancy * Known allergy or hypersensitivity to lidocaine, betamethasone, or dextrose * Mental impairment or severe psychiatric disorder that may interfere with study participation or informed consent
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What it tests

  • Betamethasone
  • Dextrose Injection
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Where

1 site
Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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