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โ† Trials
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Assessment of Residual Congestion in Acute Decompensated Heart Failure

Recruitingn/aAges 18 Years - anyAllAarhus University Hospital
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In plain words

What the trial is, and whether it could suit you

DESIGN: A prospective, multicenter, observational cohort study including 580 patients admitted for acute decompensated heart failure (ADHF). Ultrasound assessment of congestion (VExUS and LUS) will be performed serially during admission: within 48 hours of admission, at the time diuretic therapy is switched from intravenous to oral, and on the day of discharge. The discharge assessment will serve as the primary predictor. Treating physicians will be blinded to all ultrasound findings. Patients will be followed for 90 days by telephone follow-up and chart review for the primary endpoint, with extended chart review at one year for selected secondary endpoints. AIMS: To determine whether combined ultrasound assessment of venous (VExUS) and pulmonary congestion (LUS) at discharge predicts heart failure readmission and all-cause mortality in patients hospitalized with ADHF. HYPOTHESIS:

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Adults (โ‰ฅ18 years) admitted with ADHF. 2. Clinical evidence of congestion during admission, indicated by โ‰ฅ1 of the following: pitting peripheral edema, ascites, elevated jugular venous pressure, or radiologic/ultrasound evidence of pulmonary congestion. 3. Treatment with โ‰ฅ40 mg i.v. furosemide or equivalent dose loop diuretic during admission. Exclusion Criteria: 1. Pregnancy 2. Moribund 3. Solitary kidney 4. Inability to provide written consent
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What it tests

  • Not listed
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Where

3 sites
Aarhus University Hospital - Department of Cardiology
Aarhus, Denmark
Copenhagen University Hospital, Amager and Hvidovre Hospital - Department of Cardiology
Copenhagen, Denmark
Zealand University Hospital - Department of Cardiology
Roskilde, Denmark
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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