A Study of the Value of Trio Genome Sequencing in the Etiological Evaluation of Early-Onset and/or Atypical Psychiatric Disorders Without Intellectual Disability or Congenital Anomalies

Inclusion Criteria: * Index case with one or more psychiatric disorders confirmed by a psychiatrist and/or child psychiatrist, whose evaluations may be supplemented as needed as part of their care, and who meets at least ONE of the following criteria for atypicality: * Early age of onset * Unusual course of the disorder (polymorphic/fluctuating) * Treatment resistance * Disorder classified as "unspecified" by the DSM-5 with significant functional impact * Index case aged 3 to 50 years, inclusive * Consent signed by the biological parents and by the "index case, if of legal age" * Index case and their parents enrolled in or eligible for a social security program * Sample collection possible from the index case and their two known biological parents Exclusion Criteria: * Genetic testing previously performed (CGH array, targeted gene testing, gene panel, etc.) * Parent(s) and/or the index case subject to a court-ordered protective measure * The index case and his or her parents have a condition that, in the investigator's opinion, would contraindicate the subject's participation in the study * Presence of an intellectual developmental disorder confirmed by a neuropsychological test or strongly suspected clinically in the index case and/or their parents * Index case with a clear syndromic diagnosis * Index case with a psychiatric disorder already covered by a pre-indication under PFMG2025.