The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke

Inclusion Criteria: * Adults 21-65 years * Adults who smoke (defined as ≥ 5 days weekly use of either menthol or non-menthol cigarettes over the past 3 months) * Willing to provide informed consent and abstain from using nicotine products 12 hours before each visit * Willing to bring UBC to each study visit * Read, write and speak English Exclusion Criteria: * Current use of other non-combustible nicotine products (e.g., electronic \[e\]-cigarettes, HTPs; \[defined as ≥ 5 days weekly use in the past 30 days\]) * Planning to quit nicotine use and/or use of any smoking cessation medication in the past 30 days * Current diagnosis of any lung diseases (e.g., asthma, cystic fibrosis, or chronic obstructive pulmonary disease) * Self-reported unstable or significant psychiatric conditions (past/stable conditions will be allowed) * History of cardiac event or distress within the past 3 months * Deaf, hard of hearing, or have a severe motor disability * Are currently pregnant, planning to become pregnant, or breastfeeding (urine pregnancy test will be completed at each visit throughout the study)