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TG-INSIGHT With Joint POCUS, Hemostatic Potential in Patients With Severe Hemophilia A on Novel Replacement and Substitution FVIII Therapies

Recruitingn/aAges 6 Months - anyAllUniversity of Texas Southwestern Medical Center
NCT07692217 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is an observational research study to find out if there is a difference in the way children with moderate or severe hemophilia A, treated on two different types of factor replacement, form a clot and also evaluate if they develop tiny bleeds within the joint and subsequently early joint changes when receiving extended half-life factor VIII.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participants with moderate or severe HA who are on prophylaxis with either weekly, biweekly, or every 4-weeks emicizumab or weekly efanesoctocog alfa for at least 2 months. * \>6 months of age Exclusion Criteria: * Participants with active FVIII inhibitor (\>0.5 BU/mL) * Presence of an additional bleeding disorder other than hemophilia A
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What it tests

  • Half-life factor VIII based replacement therapy
  • Non-FVIII based replacement therapy
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Where

1 site
The University of Texas Southwestern Medical Center
Dallas, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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