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Taiwan Green Propolis for Blood Lipids and Body Fat in Patients With MASLD

RecruitingNAAges 18 Years - 80 YearsAllTaipei Medical University
NCT07692438 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common chronic liver condition linked to excess body fat, high blood lipids, and other metabolic problems. Taiwan green propolis is a natural health product collected by bees from plants, which has shown potential benefits for blood lipids and body fat in laboratory and animal studies. However, its effects in people with MASLD have not been well established in clinical trials. This study is a double-blind, randomized, placebo-controlled trial enrolling up to 60 adults with MASLD at Dalin Tzu Chi Hospital in Taiwan. Eligible participants are randomly assigned in a 1:1 ratio to receive either Taiwan green propolis capsules or matching placebo capsules for 12 weeks. Participants take 2 capsules before breakfast and 2 capsules before dinner each day (4 capsules per day total). Neither participants nor the research team kn

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 to 80 years * Diagnosis of hepatic steatosis (fatty liver) confirmed by abdominal ultrasound, PLUS at least one of the following metabolic risk factors: 1. Overweight or obesity: BMI \>= 23 kg/m\^2 2. Elevated waist circumference: \>= 90 cm in men or \>= 80 cm in women (South Asian and Chinese criteria) 3. Dysglycemia or type 2 diabetes: prediabetes (HbA1c 5.7-6.4%, or fasting glucose 100-125 mg/dL, or OGTT 2-hour glucose 140-199 mg/dL) OR type 2 diabetes (HbA1c \>= 6.5%, or fasting glucose \>= 126 mg/dL, or OGTT 2-hour glucose \>= 200 mg/dL, or current pharmacological treatment for type 2 diabetes) 4. Elevated triglycerides: \>= 150 mg/dL or currently on lipid-lowering therapy 5. Low HDL-C: \<= 39 mg/dL in men or \<= 50 mg/dL in women, or currently on lipid-lowering therapy 6. Elevated blood pressure: \>= 130/85 mmHg or currently on antihypertensive treatment Exclusion Criteria: * Known allergy to honey, propolis, multiple pollens, or alcohol * Psychiatric disorder or cognitive impairment * Currently pregnant or breastfeeding * Significant endocrine abnormality, or major disease of the heart, liver (other than MASLD), or kidney * Difficulty swallowing capsules * Dementia, impaired consciousness, or inability to respond to questionnaires
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What it tests

  • Taiwan green propolis capsule
  • Placebo capsule
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Where

1 site
Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Dalin, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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