Single-Dose vs. Divided-Dose G-CSF for Stem Cell Mobilization in Healthy Allogeneic Donors

Inclusion Criteria: 1. Age 18-65 years. 2. Provision of written informed consent. 3. White blood cell (WBC) count \> 2.5 × 10⁹/L. 4. Absolute neutrophil count (ANC) \> 1.5 × 10⁹/L and platelet count \> 100 × 10⁹/L. 5. Deemed suitable as a donor by the investigator based on donor physical examination and HLA matching. 6. Body weight ≥ 40 kg for females and ≥ 45 kg for males. Exclusion Criteria: 1. Currently having any disease or condition that, in the judgment of the investigator, would make the donor unsuitable for participation in this study, such as severe neurological, hepatic, renal, endocrine, cardiovascular, hematologic, gastrointestinal, respiratory, or metabolic diseases; malignancies; myeloproliferative disorders; or psychiatric illnesses. 2. Currently having an active infection requiring systemic therapy. 3. Allergy to the study drug. 4. Presence of a malignant tumor. 5. Untreated HBV infection with HBV-DNA above the lower limit of detection. 6. HIV infection. 7. Addition of any new medication within 2 weeks prior to entry into this study. 8. Female donors who are pregnant or breastfeeding.