🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

A Study of MZE782 in Adults With PKU

RecruitingPhase 2Ages 18 Years - 75 YearsAllMaze Therapeutics
NCT07694440 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the safety, tolerability, and efficacy of MZE782 in adults with Phenylketonuria (PKU).

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Key Inclusion Criteria: * Males and females 18 to 75 years old * Confirmed diagnosis of PKU * Willing and able to keep diet and protein intake consistent during the study * For some study groups, is willing and able to stop certain PKU medications before starting study treatment * For some study groups, may need to meet additional blood phenylalanine level or background-treatment requirements * Meets minimum blood phenylalanine level requirements for study group Key Exclusion Criteria: * Is pregnant, breastfeeding, or planning to become pregnant or conceive a child during the study * Medical conditions or abnormal test results that could make participation unsafe or make it difficult to complete study procedures or interpret study results * Has recently received another investigational drug * Is unable to swallow tablets or tolerate oral medication Other inclusion/exclusion criteria defined in protocol apply.
💊

What it tests

  • MZE782
  • Placebo
  • MZE782
📍

Where

9 sites
UCSF Benioff Children's Hospital Oakland
Oakland, United States
Stanford University Clinical and Translational Research Unit
Palo Alto, United States
Ann and Robert H. Lurie Children's Hospital of Chicago
Chicago, United States
Indiana University School of Medicine
Indianapolis, United States
University of Kentucky Medical Center
Lexington, United States
Clinic for Special Children
Gordonville, United States
University of Tennessee Health Science Center Le Bonheur Children's Hospital
Memphis, United States
CHRU Hôpitaux de Tours - Hôpital Bretonneau
Tours, France

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy