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Digital Course and Precision Rehabilitation for Knee Osteoarthritis and Older Adults: Integration of Multisensory Stimulation and Digital Twin Technology

RecruitingNAAges 20 Years - 80 YearsAllNational Taiwan University Hospital
NCT07695168 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Knee osteoarthritis (OA) is a common degenerative joint disease in middle-aged and older adults and is frequently associated with pain, quadriceps weakness, reduced mobility, impaired proprioception, balance deficits, and limitations in daily functional activities. Exercise therapy is recommended as a first-line conservative treatment for early to moderate knee OA; however, conventional rehabilitation programs often rely on therapist supervision and lack objective, quantitative movement monitoring, real-time feedback, and personalized adjustment for home-based training. These limitations may reduce exercise adherence and make it difficult to ensure correct movement execution outside the clinical setting. The overall aim of this study is to develop and evaluate a digital rehabilitation exercise program and user interface for individuals with arthritis, using a smart elastic knee brace in

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📋 Eligibility rules (as published)
Inclusion Criteria: (Group A: Healthy Adults) * Participants aged 20 to 80 years. * Participants who have no knee discomfort symptoms, such as knee pain or muscle weakness. (Group B: Patients with Knee Osteoarthritis) * Participants aged 50 to 80 years. * Patients diagnosed with knee osteoarthritis, classified as Kellgren-Lawrence grade 1 to grade 3. Exclusion Criteria: (Group A and B) * History of knee or hip surgery. * Systemic arthritis. * Neurological disease. * Malignant tumor. * Untreated osteomyelitis or immature skeletal development. * Pregnancy. * Inflammatory ulcer. * Deep vein thrombosis. * Excessively moist wounds. * Hemophilia. * Local infection in the treatment or assessment area. * Acute myocardial infarction. * Unstable angina. * Severe aortic stenosis. * Uncontrolled heart failure. * Acute pulmonary embolism. * Acute myocarditis or pericarditis. * Acute aortic dissection.
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What it tests

  • digital rehabilitation exercise courses combined with multisensory stimulation
  • Home exercises based on therapist education
  • Gait retraining combined with neuromuscular electrical stimulation
  • Gait retraining
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Where

3 sites
National Taiwan University Hospital
Taipei, Taiwan
School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
Taipei, Taiwan
Taipei Tzu Chi Hospital International Medical Service Center
Taipei, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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