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Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)

Recruitingn/aAges any - 18 YearsAllUniversity of Medicine and Pharmacy at Ho Chi Minโ€ฆ
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In plain words

What the trial is, and whether it could suit you

This observational patient registry aims to describe the clinical phenotypes and genetic findings of Vietnamese children with movement disorders of unknown etiology. Eligible participants are children with clinically confirmed movement disorders after evaluation by pediatric neurology specialists and after exclusion of clear acquired causes. The study will collect clinical data, neurological examination findings, available laboratory and imaging results, and video recordings of abnormal movements when consent is provided. Blood samples will be collected for whole-exome sequencing and related genetic analysis. Genetic variants will be classified according to accepted clinical genetics standards and compared with the patients' clinical phenotypes. The study is expected to improve understanding of the phenotypic and genotypic spectrum of pediatric movement disorders in Vietnam, support ge

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Children younger than 18 years old. * Patients with clinically confirmed movement disorders based on direct examination and/or video review by at least two pediatric neurology specialists. * Patients with movement disorders of unknown etiology after appropriate neurological evaluation and exclusion of clear acquired causes. * Patients evaluated or treated at University Medical Center Ho Chi Minh City or Children's Hospital 1 during the study period. * Patients and/or legal guardians who provide written informed consent for study participation and genetic testing. Exclusion Criteria: * Patients with isolated or transient primary tic disorders. * Patients with a confirmed acquired cause of movement disorder. * Patients or legal guardians who decline participation or withdraw from the study. * Patients with insufficient clinical information or unavailable biological samples for genetic analysis.
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What it tests

  • Whole-Exome Sequencing
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Where

2 sites
Children's Hospital 1, Ho Chi Minh City
Ho Chi Minh City, Vietnam
University Medical Center Ho Chi Minh City
Ho Chi Minh City, Vietnam
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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