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Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery

RecruitingPhase 4Ages 19 Years - 79 YearsAllSeoul National University Hospital
NCT07699744 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area. However, when the effect of a single-injection nerve block wears off, many patients experience sudden, intense pain known as "rebound pain". One way to prevent rebound pain is to place a thin catheter near the nerves so that local anesthetic can be given continuously for a longer period (continuous nerve block). However, this method is technically demanding and can cause problems such as catheter dislodgement, infection, and inconvenience for patients. Another simpler option is to give a single-injection nerve block together with an intravenous (IV) injection of dexamethasone, a steroid medication known to prolong the effect of nerve blocks and reduce rebound pain. The purpose of this study is to

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients aged 19 to 79 years scheduled for elective shoulder surgery under brachial plexus block and monitored anesthesia care (MAC) Exclusion Criteria: * Pre-existing neurological deficit of the brachial plexus * Emergency surgery * American Society of Anesthesiologists (ASA) physical status classification IV or higher * Contraindication or history of hypersensitivity to local anesthetics or dexamethasone * Severe pulmonary disease (e.g., chronic obstructive pulmonary disease) * Body mass index (BMI) ≥ 35 kg/m² * Long-term use of steroids * Long-term use of analgesics * Inability to cooperate or communicate * Pregnancy
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What it tests

  • Dexamethasone (IV)
  • Single-shot interscalene brachial plexus block
  • Continuous interscalene brachial plexus block
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Where

1 site
Seoul National University Hospital
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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