🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Exercise Prehabilitation in Congenital Heart Disease

RecruitingNAAges 18 Years - anyAllLiverpool Heart and Chest Hospital NHS Foundation…
NCT07700459 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Around 8-12 in every 1000 babies are born with an abnormal heart, known as a congenital heart defect (CHD). Thanks to major advances in medical and surgical care, most babies born with CHD now live into adulthood. As people with CHD get older, many need repeated heart operations. It is known from other areas of medicine that "prehabilitation" - a short, structured exercise programme completed before surgery - can improve fitness and help patients cope better with major operations. However, this approach has never been tested in adults with CHD. The investigators are running a randomised controlled trial to find out whether a prehabilitation programme can improve physical fitness before heart surgery in adults with CHD. Participants will be randomly assigned to usual care or a prehabilitation group. Those in the prehabilitation group will follow a tailored, supervised exercise plan for

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Adults with congenital heart disease requiring cardiac surgery via sternotomy or thoracotomy. * Capacity to provide informed consent. * Ability and willingness to engage in exercise-based interventions. * Peak VO2 \<30ml/kg/min at preoperative exercise assessment. * Participant reached peak VO2 in preoperative exercise assessment (RER \>1.0). * Ability to communicate in English. Exclusion Criteria: * Surgery is scheduled for a date that precludes participation in the programme - surgical date is \<9 weeks away. * Pregnancy of \<6 months postpartum. * History of pneumothorax within the last 3 months. * Resting oxygen saturations \<94%. * Uncorrected right-to-left shunt with exercise. * Fontan physiology. * Pulmonary hypertension. * Critical valvular obstruction. * Sustained ventricular arrhythmia. * Severe aortic dilatation (\>45mm in Marfan syndrome or hereditary aortopathy, \>50mm in bicuspid or tricuspid aortic valves). The oldest person operated upon by the ACHD service was 78 years old. Upper age is not an exclusion criteria.
💊

What it tests

  • Exercise prehabilitation
📍

Where

1 site
Liverpool Heart and Chest Hospital NHS Foundation Trust
Liverpool, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy