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Kodo Millet Porridge and Its Effects on Gut Health and Metabolic Syndrome

RecruitingNAAges 20 Years - 60 YearsAllJSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCAT…
NCT07703371 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Dietary fiber are components in foods that are not digested by human gastrointestinal enzymes (alpha amylase and alpha glucosidase) but are instead broken down and fermented by gut microbes. The byproducts generated during fermentation in the large intestine, primarily short-chain fatty acids (SCFA), bile acids, indoles, and their derivatives, circulate through the circulatory system to the liver, lungs, brain, adipose tissue, and muscles, where they modulate metabolism (suppress lipogenesis and alleviate insulin resistance) and immune function. Individuals who are overweight or obese frequently exhibit gut dysbiosis, characterized by lower SCFA producing commensals. This condition predisposes them to metabolic disorders such as insulin resistance, dyslipidemia, and hypertension, and contributes to conditions including type 2 diabetes, cardiovascular disease, and metabolic dysfunction-as

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📋 Eligibility rules (as published)
Inclusion Criteria * Adults aged 20-60 years. * Willingness to provide informed consent. * Willingness to consume Kodo millet porridge daily for 12 weeks. * No planned changes in diet or physical activity during the study. * Overweight or obese (BMI ≥ 25 kg/m²), placing them at risk for metabolic disorders. Exclusion Criteria * Known allergies to millet or any porridge ingredients. * Individuals who are taking on-counter dietary fiber and probiotics supplements * History of any chronic gastrointestinal diseases (e.g., IBD, gastritis, irritable bowel syndrome). * Pregnant or lactating women. * Antibiotic use in last 3 months. * Alcohol abuse, more than 2 drink per day * Presence and usage of medications for any serious chronic illnesses, including uncontrolled diabetes (HbA1c \> 9), cardiovascular disease (aldosterone antagonists, alpha blockers, alpha-beta blockers, anticoagulants, antiplatelets, angiotensin-converting enzyme inhibitors, angiotensin 2 receptor blockers, beta blockers, calcium channel blockers, diuretics, digoxin) , renal disease, neurological or mental disorders, coagulation disorders, and cancer.
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What it tests

  • Kodo Millet Porridge Beverage
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Where

1 site
JSS Medical College, JSS Academy of Higher Education & Research(JSSAHER).
Mysore, India
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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