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Internal Organ and Musculoskeletal Assessment in Hypothyroidism (HYPOMORPH)

Recruitingn/aAges 18 Years - 59 YearsAllAndijan State Medical Institute
NCT07707830 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

HYPOMORPH is a hospital-based observational cross-sectional study designed to comprehensively characterise internal-organ morphometry and musculoskeletal status in adults with previously diagnosed hypothyroidism receiving routine medical care in Andijan, Uzbekistan. Approximately 500 adults aged 18-59 years will be included. Participants undergo standardised clinical and anthropometric assessment, ultrasonographic examination of the liver, pancreas and both kidneys, measurement of handgrip strength, and assessment of physical performance using the Five Times Sit-to-Stand Test and 4-m gait speed test. Sarcopenia risk and habitual physical activity are assessed using the SARC-F questionnaire and the International Physical Activity Questionnaire-Short Form (IPAQ-SF), respectively. Serum thyroid-stimulating hormone (TSH) and free thyroxine (FT4) concentrations are measured to characterise t

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18-59 years. * Previously established diagnosis of hypothyroidism. * Receiving routine outpatient or inpatient care at participating healthcare institutions. * Ability to undergo ultrasonographic, anthropometric and functional assessments. * Provision of written informed consent. Exclusion Criteria: * Pregnancy or lactation. * History of thyroid malignancy. * Acute infectious or inflammatory disease at the time of enrolment. * Severe decompensated cardiovascular, hepatic or renal disease preventing study procedures. * Neurological or musculoskeletal disorders that preclude functional testing. * Refusal or inability to provide written informed consent.
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What it tests

  • Comprehensive Morphometric and Functional Assessment
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Where

1 site
Andijan State Medical Institute
Andijan, Uzbekistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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