Tegoprazan Versus Lansoprazole for Endoscopic Ulcer Healing in Bleeding Peptic Ulcers

Inclusion Criteria: * Subjects aged 18 years and over. * Subjects with upper gastrointestinal bleeding caused by peptic ulcers diagnosed by gastroscopy. * Willing to participate in the entire clinical study process, including: 1. . Fluid resuscitation and blood transfusion, if necessary, 2. . High-dose PPI therapy for 72 hours, 3. . Gastroscopy within 24 hours of hospital admission and endoscopic hemostatic therapy, if necessary, 4. . Lansoprazole 30 mg or tegoprazan 50 mg therapy for 14 days, 5. . Treatment for H. pylori infection if positive, 6. . Repeat gastroscopy after 14 days of treatment to assess the progress of therapy. Exclusion Criteria: * Subjects with a history of allergy to tegoprazan or lansoprazole * Subjects with a history of allergy to tegoprazan or lansoprazole. * Subjects with ulcers caused by gastric or duodenal cancer. * Subjects with comorbidities such as chronic kidney disease stage 3 or higher and decompensated liver cirrhosis. * Patients who are heavy alcohol drinkers and have used chemotherapy drugs, bisphosphonates, or potassium supplements in the past 2 weeks.