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Remineralizing Effect of Nano-eggshell, Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), and Sodium Fluoride on Initial Enamel Caries

RecruitingNAAges 15 Years - 20 YearsAllMansoura University
NCT07711132 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled clinical trial aims to evaluate and compare the remineralizing effect of nano-eggshell varnish, CPP-ACP paste (GC Tooth Mousse), and sodium fluoride varnish on initial enamel caries among adolescents aged 15-20 years. Participants will be randomly allocated into three groups. Remineralization and caries activity will be assessed using DIAGNOdent readings, International Caries Classification and Management System (ICCMS) criteria, and the decayed, missed, and filled surfaces (DMFS) index over a 12-month follow-up period.

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📋 Eligibility rules (as published)
Inclusion Criteria: Patients' ages should be 15-20 years. Patients should have at least three to four teeth with ICDAS II scores of 1-2. Patients should have moderate-to-high caries risk. Exclusion Criteria: Known hypersensitivity to one of the components of the material under study. Systemic disorders or medication interfering with normal salivary flow.
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What it tests

  • nano-eggshell varnish
  • Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP)Dental Paste
  • Sodium Fluoride Varnish (5%)
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Where

1 site
Faculty of Dentistry, Mansoura University
Al Mansurah, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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