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Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas

RecruitingNAAges 18 Years - 40 YearsFemaleInsel Gruppe AG, University Hospital Bern
NCT07711743 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas. Researchers want to determine how deeply ABC affects ovarian tissue and to generate data on the safety of this surgical technique. Participants will undergo standard laparoscopic surgery for ovarian endometriomas. During the planned surgical procedure, Argon Beam Coagulation will be applied to the ovarian surface according to the study protocol. The treated tissue will subsequently be excised as part of the planned surgery and analyzed histologically to measure the depth of tissue penetration.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female patients aged 18-40 years. * Indication for surgical treatment of ovarian endometrioma based on clinical symptoms and/or imaging findings. * Diagnosis of ovarian endometrioma ≥3 cm confirmed by preoperative imaging (ultrasound and/or MRI). * Planned laparoscopic cystectomy. * Written informed consent. Exclusion Criteria: * Expected lack of compliance or inability to understand the study procedures. * Previous surgical procedures on the affected ovary. * Recurrent ovarian endometrioma. * Pregnancy or breastfeeding. * Participation in another interventional clinical study that may influence study outcomes, such as anti-Müllerian hormone (AMH) levels or pregnancy.
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What it tests

  • Argon Plasma Coagulation
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Where

1 site
University Hospital of Obstetrics and Gynecology, Inselspital Bern
Bern, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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