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Study of XmAb412 in Healthy Participants

RecruitingPhase 1Ages 18 Years - 55 YearsAllXencor, Inc.
NCT07713485 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This Phase 1 Study will evaluate the safety, tolerability, pharmacokinectics and pharmacodynamics of XmAb412 in healthy adult participants

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-55 years old * Must be in good health with no significant medical history * BMI 18-35 kg/m2 * Contraceptive use consistent with local regulations * Able and willing to provide written informed consent Exclusion Criteria: * Any physical condition that prohibits study completion * Known hypersensitivity to the trial intervention or any of its components * HIV, hepatitis B and hepatitis C positive * Clinically significant abnormal ECG * Use of other investigational products within 5 half lives from Screening * Blood or plasma donation within 60 days from Screening * Pregnant or breastfeeding Other protocol defined inclusion/exclusion criteria apply
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What it tests

  • XmAb412 Monoclonal Bispecific Antibody
  • Placebo
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Where

2 sites
Xencor Investigative Site
Joondalup, Australia
Xencor Investigative Site
Nedlands, Australia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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