🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Screening, Classification, and Outcome Prediction Ensemble Using Orbital MRI for Thyroid Eye Disease: The TED SCOPE National Multicenter Registry Study

Recruitingn/aAges 18 Years - 75 YearsAllShanghai Changzheng Hospital
NCT07716397 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to prospectively validate the efficacy of an AI multimodal model constructed based on multi - sequence orbital MRI in the diagnosis, activity and severity assessment, and prognosis prediction of thyroid - associated ophthalmopathy (TAO) in real - world clinical scenarios. The main questions it aims to answer are: Can AI models accurately assess the presence, activity, and severity of Thyroid-Associated Orbitopathy (TAO)? Can AI models predict the prognosis of TAO? Researchers will compare the diagnostic accuracy of the AI model for TAO patients and healthy subjects to evaluate its diagnostic performance. Participants will undergo a standardized, study - specific multimodal orbital MRI scan (sequences include T1WI, T2WI, STIR, and research sequences such as Magic, IDEAL - IQ, DWI, ASL, CEST). And will systematically acquire ocular ultrasound image

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * TAO patient group * Age between 18 and 75 years old, regardless of gender. * Patients with thyroid eye disease who meet the disease staging and grading criteria specified in diagnostic guidelines such as those of Bartley, CAS, and EUGOGO. * The patient has planned or received thyroid-related treatment, and the condition is relatively stable. * Voluntarily participate in this study and sign the informed consent form. Control group: ① Healthy volunteers matched with the TAO group in terms of age and gender. ② Voluntarily participate in this study and sign the informed consent form. Exclusion Criteria: * TAO patient group: * Pregnant or lactating women. * Patients with other orbital lesions. ③ Having contraindications for MRI examination (such as non - compatible metal implants in the body, claustrophobia, etc.). ④ The patient has previously received orbital radiotherapy or orbital surgery (except for patients who need to collect tissue specimens). ⑤ Comorbid with other severe systemic diseases (such as uncontrolled heart failure, liver and kidney failure) or mental illnesses, and unable to cooperate to complete the study. ⑥ Participated in other clinical trials that may interfere with the results of this study within 3 months. Control group: Same as the exclusion criteria 1 - 6 for the TAO patient group
💊

What it tests

  • MRI scan，ocular ultrasound
📍

Where

1 site
Shanghai Changzheng Hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy