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Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy

RecruitingPhase 4Ages 18 Years - 59 YearsAllUniversidade Federal de Sergipe
NCT07717684 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy. The study aims to determine whether remimazolam leads to a different time to loss of consciousness than propofol. The main question it aims to answer is: Does remimazolam change the time to loss of consciousness compared with propofol during anesthesia induction? Researchers will compare remimazolam with propofol to evaluate the time required for participants to lose consciousness. The study will also compare blood pressure, heart rate, and other safety outcomes during anesthesia induction. Participants will: * Be randomly assigned to receive either remimazolam or propofol for anesthesia induction. * Receive standard monitoring and anesthesia care throughout surgery. * Have their time to loss of consciousness, vital signs, and any a

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18 years or older. * American Society of Anesthesiologists (ASA) physical status I, II or III. * Scheduled to undergo elective laparoscopic cholecystectomy under Total Intravenous Anesthesia (TIVA). Exclusion Criteria: * Patients younger than 18 years or older than 60 years * American Society of Anesthesiologists (ASA) physical status IV to V * Body Mass Index (BMI) \< 17.5 kg/m² or \> 35 kg/m² * Hemodynamically unstable patients * Altered or impaired renal or hepatic function * Neuromuscular disorders * History of alcohol or drug dependence * History of allergy or hypersensitivity to any of the anesthetic medications utilized in the protocol
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What it tests

  • Remimazolam
  • Propofol
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Where

1 site
Hospital Univeritário da Universidade Federal de Sergipe
Aracaju, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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