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Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic Retainers

RecruitingNAAges 18 Years - 40 YearsAllUniversidad de Murcia
NCT07718061 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

After completion of orthodontic treatment, a retention phase is required to prevent relapse of tooth malposition. Fixed retention in the mandibular anterior region is commonly used. This type of retainer is bonded to the lingual surfaces of the canines and incisors and may hinder oral hygiene, thereby promoting bacterial plaque accumulation and gingival inflammation. Currently, probably due to the increasing use of clear aligner therapy, clear removable Essix-type retainers are becoming more widely used. Since these retainers can be removed by the patient, they may facilitate oral hygiene. However, studies assessing gingival health and the composition of the subgingival microbiota in patients wearing orthodontic retainers remain scarce. Therefore, the aim of this study will be to assess the composition of the gingival sulcus microbiota and gingival health in patients wearing fixed or r

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📋 Eligibility rules (as published)
Inclusion Criteria: * Treatment involving both dental arches * Permanent dentition with at least 24 teeth * Treatment duration longer than 12 months * Treatment using the Versatile MBT system with a 0.022-inch slot Exclusion Criteria: * Patients with systemic disease or taking medications that may affect periodontal health * Inadequate restorations or active carious lesions * iodontal disease * Plaque index greater than 20% before placement of the retainer or during the study * Use of oral antiseptics within the previous 6 months or during the study period * Use of antibiotics within the previous 14 days or during the study period * Smokers * Pregnant or breastfeeding women * Presence of open gingival embrasures, crowding, or dental malposition in the mandibular anterior region after orthodontic treatment
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What it tests

  • Fixed Orthodontic Retainer
  • Removable Essix-Type Orthodontic Retainer
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Where

1 site
University Dental Clinic
Murcia, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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