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Risk Factors for Mesh Infection After Abdominal Wall Reconstruction

Recruitingn/aAges 18 Years - anyAllMinia University
NCT07725718 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Abdominal wall reconstruction (AWR) with mesh is the standard repair for ventral, incisional, parastomal and complex abdominal wall defects, but mesh-related infection remains one of its most serious complications - prolonging hospital stay, often requiring reoperation or removal of the mesh, and increasing the risk of hernia recurrence. Reported infection rates vary widely, and the independent contribution of individual risk factors remains uncertain, in large part because much of the existing evidence comes from retrospective series with inconsistent outcome definitions. This single-centre, prospective observational cohort study will enrol consecutive adults undergoing elective or urgent AWR with synthetic, biosynthetic or biological mesh at a tertiary referral hernia unit. Participants will be followed for 12 months on a fixed schedule (7-10 days, 30 days, 90 days, 6 months and 12 mo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged ≥18 years. * Undergoing elective or urgent abdominal wall reconstruction with implantation of synthetic, biosynthetic or biological mesh for a ventral, incisional, parastomal or complex abdominal wall defect. * Able and willing to provide written informed consent and to attend scheduled follow-up. Exclusion Criteria: * Suture-only repair without mesh. * Inguinal or femoral (groin) hernia repair. * Active systemic sepsis or established intra-abdominal mesh infection at the time of index surgery. * Mesh placed solely for a non-reconstructive indication (e.g. temporary abdominal closure or planned re-look without definitive reconstruction). * Estimated life expectancy \< 12 months or inability to complete the minimum follow-up. * Patient declines participation.
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What it tests

  • Not listed
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Where

1 site
Minia University Hospitals - Department of Surgery, Faculty of Medicine, Minia University
Minya, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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