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โ† Trials
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Performance After Cardiac Ablation in Endurance Athletes for Atrial Fibrillation

RecruitingNAAges 18 Years - 80 YearsAllUniversity Hospital of Leuven Leuven
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In plain words

What the trial is, and whether it could suit you

The relationship between exercise and atrial fibrillation (AF) seems to follow a J-shaped curve: while moderate activity reduces AF risk, both insufficient and excessive endurance exercise increase susceptibility. In athletes, standard treatments such as antiarrhythmic drugs often provide only partial symptom control and may impair performance through fatigue, chronotropic incompetence and side effects. Pulmonary vein isolation (PVI) may offer a more definitive therapeutic option but carries risks of atrial fibrosis, stiffening, and altered autonomic regulation, which may also influence exercise capacity. The investigators hypothesize that ablation will have a significant impact-either beneficial or detrimental-on the physical performance of athletes with AF. However, existing evidence is limited to small studies with inconsistent findings, underscoring the need for a dedicated study. T

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18-80 years * Participation in endurance sports (โ‰ฅ4 hours/week) * Diagnosis of atrial fibrillation * Capturing training data through commercially available platforms (e.g. Strava, TrainingPeaks, โ€ฆ) or willingness to start collecting training data and working with these commercially available platforms prospectively Exclusion Criteria: * No training data available * History of cardiovascular disease (including ischemic heart disease, cardiomyopathy, valvular heart disease, primary electrical disorders, or congestive heart failure) * Active smoking
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What it tests

  • Ablation
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Where

5 sites
St. Vincent's Hospital
Melbourne, Australia
Universitair Ziekenhuis Antwerpen
Antwerp, Belgium
ZOL Genk
Genk, Belgium
Jessa Hospital, Department of Cardiology
Hasselt, Belgium
UZ Leuven
Leuven, Belgium
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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