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Correlation Between Colour of Defect and Enamel Breakdown in First Permanent Molars With Molar Incisor Hypomineralisation (MIH)

Recruitingn/aAges 5 Years - 8 YearsAllUniversity of Basel
NCT07727200 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cheese molars (MIH) can be recognized not only by their colour abnormalities but also by the enamel breakdown. Clinical management of those teeth may become challenging by the chronic hypersensitivity, that makes various steps during treatment, such as pain control or light curing of any type of composite restorations, difficult or even impossible, despite profound local anaesthesia. The aim of this study is to determine the relationship between colour of the defect and loss of ename in the affected teeth. A correlation between colour of the defect and risk of enamel breakdown could enable early prognosis leading to preventive measures in order to delay or even avoid completely any breakdown of the enamel. Children diagnosed with MIH on their first permanent molars of different severity are matched to children with sound molars. They are identified by the annual school dental check-up an

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📋 Eligibility rules (as published)
MIH Study Group Inclusion Criteria: * Children between 5 to 8 years with MIH molars with or without hypersensitivity according to the MIH-TN Index (Bekes et al 2016) * Children with first molars in occlusion * Children fit and healthy Exclusion Criteria: * MIH first permanent molars that have already received any kind of dental treatment * Children diagnosed with HSPM (hypomineralised second primary molars) * Children older than 8 years - Children younger than 5 years * Children with any cranio-facial and/or other developmental dental defects * Children diagnosed with parafunctions (attrition/ erosion) * Children and/or parents who did not consent to the study * Children with MIH teeth that show clinically visible enamel loss during the eruption * Children without the first molars in occlusion Non- MIH Control Group Inclusion Criteria: * Children between 5 to 8 years with no clinically affected molars- Page 4 of 5 * Children fit and healthy Exclusion Criteria: * Children who have already received any kind of dental treatment on their permanent or primary teeth * Children diagnosed with MIH or any other disease of the teeth * Children older than 8 years * Children younger than 5 years * Children with any cranio-facial and/or other developmental dental defects * Children diagnosed with parafunctions (attrition/ erosion) * Children and/or parents who did not consent to the study
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What it tests

  • Not listed
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Where

1 site
University Centre for Dental Medicine
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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