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Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region

RecruitingNAAges 18 Years - 45 YearsAllMansoura University
NCT07727655 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized clinical trial will evaluate the effect of using an enamel matrix derivative during immediate dental implant placement in the mandibular molar region. Patients who require extraction of a non-restorable mandibular molar and immediate implant placement will be randomly assigned to receive an implant placed with enamel matrix derivative or without enamel matrix derivative. Clinical and radiographic outcomes, including implant stability and peri-implant bone changes, will be assessed over a follow-up period of six months. The results of this study aim to determine whether the use of enamel matrix derivative improves osseointegration and healing around immediate dental implants.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients with non-restorable mandibular molar requiring dental extraction. 2. Patient medically free from systemic diseases that absolutely contraindicate implant surgery. 3. Age range: from (18 to 45) years. 4. Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration (8-12mm). 5. Extraction sockets with intact bony walls and interradicular bone. 6. Jumping gap more than 2mm. 7. Patients with good oral hygiene. 8. Patients willing to participate in the study's follow-up intervals. Exclusion Criteria: 1. Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement. 2. smoker patients. 3. Pregnant patients. 4. Patients with para-functional habits (bruxism and clenching)
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What it tests

  • Enamel Matrix Derivative (Emdogain)
  • Immediate Dental Implant Placement
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Where

1 site
Faculty of Dentistry, Mansoura University - Oral and Maxillofacial Surgery Department
Al Mansurah, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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