🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Pregnant Women With Hypertensive Disorders of Pregnancy

Recruitingn/aAges 18 Years - anyFemaleJosip Juraj Strossmayer University of Osijek
NCT07728656 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Hypertensive disorders of pregnancy are associated with endothelial dysfunction and increased maternal and fetal morbidity. Endothelial extracellular vesicles (EEVs) have emerged as promising biomarkers of endothelial activation; however, their relationship with blood pressure and endothelial function during pregnancy remains incompletely understood. This observational case-control study aims to compare circulating EEV concentrations between normotensive pregnant women and pregnant women with hypertensive disorders of pregnancy. The study will also investigate the associations between EEV levels, blood pressure, microvascular endothelial function assessed by laser Doppler flowmetry, and circulating biomarkers of endothelial activation. The findings may improve understanding of endothelial injury during pregnancy and support the development of non-invasive biomarkers for early detection a

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Pregnant women aged ≥18 years. * Singleton pregnancy. * Ability to provide written informed consent. * Normotensive pregnancy or diagnosis of gestational hypertension or preeclampsia according to current clinical guidelines. * Ability to comply with study procedures. Exclusion Criteria: * Chronic hypertension diagnosed before pregnancy. * Multiple pregnancy. * Pre-existing diabetes mellitus. * Chronic kidney disease. * Autoimmune disease. * Known cardiovascular disease. * Active infection or inflammatory disease. * Malignancy. * Inability or unwillingness to provide informed consent.
💊

What it tests

  • Not listed
📍

Where

1 site
Faculty of Medicine Osijek
Osijek, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy