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Clinical Effects of Intraoperative Heat and Moisture Exchange Systems During Thoracic Surgery: A Prospective Observational Cohort Study

Recruitingn/aAges 18 Years - 75 YearsAllMarmara University
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In plain words

What the trial is, and whether it could suit you

General anesthesia with endotracheal intubation bypasses the physiological warming and humidification functions of the upper airway, allowing cold and dry gases to reach the lower respiratory tract. This may impair mucociliary clearance, increase secretion viscosity, promote atelectasis, and contribute to postoperative pulmonary complications (PPCs). Patients undergoing thoracic surgery, particularly those requiring one-lung ventilation (OLV), are at increased risk for PPCs because of altered ventilation-perfusion matching, reduced functional residual capacity, and impaired secretion clearance. Although respiratory gas humidification is routinely used during anesthesia, evidence regarding the comparative clinical effects of active heated humidification (AHH) and passive heat and moisture exchangers (HMEs) during thoracic surgery remains limited. This prospective observational cohort st

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18 to 75 years * Elective video-assisted thoracoscopic surgery (VATS) * Lung resection requiring general anesthesia * Planned one-lung ventilation * Written informed consent Exclusion Criteria: * Emergency surgery * Pregnancy * Preoperative mechanical ventilation * Previous enrollment * Refusal to participate
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What it tests

  • Active Heated Humidification
  • Heat and Moisture Exchanger
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Where

1 site
Marmara University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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