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Digital Solutions for Predicting the Biological Mechanisms of Alzheimer's Disease Through the Analysis of Risk Factors

RecruitingNAAges 18 Years - anyAllIRCCS Centro San Giovanni di Dio Fatebenefratelli
NCT07731191 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Population ageing is one of the main factors responsible for the global increase in the prevalence of dementia. Recent evidence suggests that modifiable risk factors, such as cardiovascular disease and lifestyle, may increase the risk of developing dementia and contribute to its progression. Furthermore, the use of non-invasive plasma biomarkers enables the identification of individuals with neurodegenerative diseases, even in the prodromal stage. However, the relationship between the cumulative burden of risk factors and plasma biomarkers is still poorly understood. The main objective of this study is to identify and estimate the risk associated with modifiable and non-modifiable predictors (risk factors) linked to the development of Alzheimer's disease (AD) and non-AD dementia, as well as biological alterations consistent with AD or non-AD, through the development of a predictive tool

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female subjects aged more than 18 years at the time of signing the informed consent form; * Subjects with MCI or SCD who, at the time of their first visit, did not have a clinical diagnosis of dementia (MMSE ≥ 24); * Smartphone user. Exclusion Criteria: * Age younger than that stated in the inclusion criterion; * Inability to understand.
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What it tests

  • Digital solution for the prediction of the biological mechanisms of Alzheimer's disease through the analysis of risk factors
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Where

2 sites
ASST Spedali Civili di Brescia
Brescia, Italy
IRCCS Istituto Centro San Giovanni Di Dio - Fatebenefratelli
Brescia, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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