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Metabolic Liver Disease in Newly Diagnosed People Living With HIV (MASHIV-TR)

Recruitingn/aAges 18 Years - anyAllYaşar Bayındır, MD
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In plain words

What the trial is, and whether it could suit you

This study aims to identify the risk factors that lead to the development of metabolic liver disease in people who have been newly diagnosed with HIV. The research will take place across 9 centers in Türkiye and plans to include 250 newly diagnosed individuals with HIV, alongside 161 healthy individuals without HIV as a control group. Participants will have their liver health checked when they first join the study (baseline) and then once a year for up to 5 years (at 12, 24, 36, 48, and 60 months). The main goal of these visits is to monitor their metabolic health and understand who is at risk of developing a fatty liver condition known as MASLD (Metabolic dysfunction-Associated Steatotic Liver Disease). During each visit, the research team will collect information about the participants' general health, including their height, weight, medical and family history, lifestyle habits, and

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria (For the Patient Group / Newly Diagnosed HIV+): * Citizens of the Republic of Türkiye * Adults (≥ 18 years of age) * Confirmed Anti-HIV positive (Newly diagnosed) * Patients who are initiating Antiretroviral Therapy (ART) Inclusion Criteria (For the Healthy Control Group / HIV-): * Citizens of the Republic of Türkiye * Adults (≥ 18 years of age) * Confirmed Anti-HIV negative Exclusion Criteria: * There are no specified exclusion criteria for this study.
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What it tests

  • FibroScan (Transient Elastography)
  • Hepatobiliary Ultrasonography (USG)
  • Clinical and Laboratory Monitoring
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Where

11 sites
Guven Hospital
Ankara, Turkey (Türkiye)
Adana Acıbadem Hospital
Adana, Turkey (Türkiye)
Cukurova University, Faculty of Medicine
Adana, Turkey (Türkiye)
Hacettepe University, Faculty of Medicine
Ankara, Turkey (Türkiye)
Akdeniz University, Faculty of Medicine
Antalya, Turkey (Türkiye)
Dicle University, Faculty of Medicine
Diyarbakır, Turkey (Türkiye)
Gaziantep University, Faculty of Medicine
Gaziantep, Turkey (Türkiye)
Health Sciences University Hamidiye Faculty of Medicine
Istanbul, Turkey (Türkiye)

…and 3 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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