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Blood Pressure Response to Exercise and Aortic Stiffness in Patients With Cardiovascular-Kidney-Metabolic Syndrome

Recruitingn/aAges 18 Years - anyAllKaramanoğlu Mehmetbey University
NCT07737561 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cardiovascular-Kidney-Metabolic (CKM) syndrome is a recently defined clinical syndrome characterized by the coexistence and interaction of cardiovascular disease, chronic kidney disease, and metabolic disorders, including obesity, dyslipidemia, insulin resistance, and type 2 diabetes mellitus. Individuals with CKM syndrome commonly exhibit vascular dysfunction, endothelial impairment, arterial stiffness, and an increased risk of cardiovascular morbidity and mortality. Although exaggerated blood pressure response during exercise has been recognized as an early marker of future hypertension and adverse cardiovascular outcomes, its relationship with aortic stiffness in patients with CKM syndrome has not been adequately investigated. The aim of this observational study is to evaluate the association between blood pressure response during a clinically indicated exercise stress test and aorti

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📋 Eligibility rules (as published)
Inclusion Criteria: * Willing and able to provide written informed consent. * Aged 18 years or older. * Diagnosis of Cardiovascular-Kidney-Metabolic (CKM) syndrome. * Referred by a cardiologist for a clinically indicated exercise stress test as part of routine clinical care. * Able to perform an exercise stress test. Exclusion Criteria: * Physical disability or any medical condition that precludes performing an exercise stress test. * Diagnosis of major depressive disorder
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What it tests

  • Not listed
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Where

1 site
Karaman Training and Research Hospital
Karaman, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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