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Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease

RecruitingNAAges 18 Years - anyAllMedical University of Lodz
NCT07746102 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases. There is credible evidence that intentionally producing periods of ischemia provides protection of the myocardium and blood vessels against subsequent ischemic injury. The examination will be performed during hospitalization in the Department of Nephrology, Hypertension, Transplantology and Internal Diseases and will last 4 days. On the first day, blood pressure will be measured using an automatic blood pressure monitor, radial artery pulse, blood saturation will be measured using a pulse oximeter, and approximately 6 ml of venous blood will be collected from the elbow bend area for laboratory tests. Then, compression of the lower limb below the knee will be performed using a blood pr

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📋 Eligibility rules (as published)
Inclusion Criteria: * obtaining the patient's voluntary, informed consent to participate in the experiment, * chronic kidney disease in stages G1-G5, * women and men over 18 years of age. * failure to meet the qualification criteria for participation in the study, * consciousness disorders, * heart failure (NYHA IV), * severe anemia (Hb concentration\<8g/dL), * features of muscle cell damage (e.g. rhabdomyolysis), * peripheral circulation disorders, peripheral vascular diseases. Exclusion Criteria: \-
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What it tests

  • Preconditioning with control ischemic episodes
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Where

2 sites
Medical University of Lodzi
Lodz, Poland
Medical University of Lodzi
Lodz, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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