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Retrospective Analysis of Early Gastric Cancer Patients Based on Prospective Clinical Dataset

Recruitingn/aAges 18 Years - 90 YearsAllBeijing Friendship Hospital
NCT07747688 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The goal of this retrospective observational cohort study is to describe the real-world clinicopathological characteristics, evolving treatment patterns, and long-term oncological outcomes of early gastric cancer (EGC) patients in China, utilizing a large prospective clinical database. The main questions it aims to answer are: How do different treatment modalities, including endoscopic resection, laparoscopic surgery, open surgery, and combined laparoscopic-endoscopic approaches, influence the long-term survival (Overall Survival and Disease-Free Survival) and recurrence patterns in Chinese EGC patients? What are the key clinicopathological factors affecting prognosis in this population? This study will retrospectively enroll approximately 5000 patients with histopathologically confirmed gastric adenocarcinoma staged as early gastric cancer (per AJCC 8th edition) from the information d

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * patients aged between 18 and 90 years; * preoperative endoscopic biopsy-confirmed gastric adenocarcinoma; * clinical stage early gastric (cT1NxM0) cancer according to the AJCC 8th edition TNM staging system; * patients who have signed a broad informed consent. * Received primary treatment (including endoscopic resection, laparoscopic surgery, open surgery, or combined laparoscopic-endoscopic approach) at Beijing Friendship Hospital. Exclusion Criteria: * pregnant or breastfeeding women; * Preoperative or intraoperative diagnosis remained indeterminate due to insufficient pathological or imaging evidence, such that the patient could not be clearly classified as early gastric cancer prior to treatment; * Critical clinical data were severely incomplete or missing๏ผ› * Completely lost to follow-up with no available information to confirm survival status.
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What it tests

  • Clinical Data Collection
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Where

1 site
Beijing Friendship Hospital, Capital Medical University
Beijing, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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