🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Investigating the Mechanisms of Decision-Making Using Non-Invasive Brain Stimulation

RecruitingNAAges 18 Years - 40 YearsAllWuerzburg University Hospital
NCT07749378 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This study aims to investigate which of two brain regions is important for which decision-making strategy. The investigators suppose that one brain region - the \*striatum\* - is important for repeatedly choosing objects that have previously been paired with rewards (strategy 1). They suppose that a different region - the \*hippocampus\* - is important for extending such reasoning to RELATED objects (strategy 2). The investigators will repeatedly ask young and healthy subjects to choose between two objects. The two objects are repeatedly drawn from a pool of seven. Relations between the seven objects have been learned on the first day of the experiment. The investigators will record subjects' choices and will use an automated way to assess the extent to which any given subject uses either decision-making strategy. * On one day, subjects will perform the task while their right hippocamp

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * No diagnosis of any neurological or psychiatric disease Exclusion Criteria: * Severe neuropsychiatric or unstable systemic disease * Severe sensory or cognitive impairment or musculoskeletal dysfunction that would prevent subjects from understanding the task instructions or executing the tasks * Implanted medical devices * Diagnosis of epilepsy or history of one or more epileptic seizure(s) * Pieces of metal in/around the head * Regular consumption of narcotics (also excluded: cannabis within past month, alcohol abuse or dependence) * Pregnancy and breast feeding * Incapability of giving informed consent * Left-handedness Subjects included in the study will be excluded from analyses if their datasets are incomplete. To ensure full counterbalancing, excluded subjects will be replaced by new ones.
💊

What it tests

  • Hippocampal intermittent-theta burst stimulation
  • Striatal intermittent-theta burst stimulation
  • High-frequency control stimulation with striatal electrode set-up
  • High-frequency control stimulation with hippocampal electrode set-up
📍

Where

1 site
University Hospital Würzburg (UKW)
Würzburg, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy