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A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset

Recruitingn/aAges 18 Years - 90 YearsAllBeijing Friendship Hospital
NCT07749989 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This retrospective, observational cohort study aimed to establish a comprehensive research cohort utilizing a large-scale prospective clinical registry. The primary objectives were to characterize the real-world demographic profiles, clinical features, psychological characteristics, and treatment patterns of Chinese patients with gastroesophageal reflux disease (GERD), as well as to evaluate post-treatment improvements in both GERD symptoms and psychological well-being. The study retrospectively enrolled approximately 5,000 patients with a confirmed diagnosis of GERD, with data derived from the prospective registry of the National Clinical Research Center for Digestive Diseases. Investigators systematically extracted data on baseline demographics, clinical presentations, objective diagnostic findings, preoperative psychological status, surgical complications, and longitudinal follow-up o

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged between 18 and 90 years old. * Patients were required to present with at least one typical symptom of gastroesophageal reflux disease (GERD)-such as heartburn, regurgitation, or non-cardiac chest pain-and to have presented to Beijing Friendship Hospital for the evaluation and management of these symptoms. * Received treatment, including pharmacological therapy and anti-reflux surgery, at Beijing Friendship Hospital. * Voluntary signing of informed consent, agreeing to the use of clinical information for future research. Exclusion Criteria: * Female patients who were pregnant or lactating. * Patients with significantly incomplete or missing critical clinical data. * Patients with an equivocal or unconfirmed diagnosis of GERD. * Current neurologic or cognitive impairment, which would preclude ability to obtain informed consent. * Refusal to participate in the study.
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What it tests

  • Clinical Data Collection
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Where

1 site
Beijing Friendship Hospital, Capital Medical University
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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