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Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases

RecruitingNAAges 6 Months - 5 YearsAllMinia University
NCT07750379 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Laryngomalacia is the most common congenital laryngeal anomaly in children and is frequently associated with aspiration. This randomized controlled study aims to assess the role of proton pump inhibitor (PPI) therapy in reducing the incidence of aspiration in pediatric patients with laryngomalacia. Eligible participants will be randomly assigned to either a PPI treatment group or a control group. Clinical and swallowing assessments will be performed to compare aspiration incidence and swallowing outcomes between the two groups

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Children diagnosed with laryngomalacia by laryngoscopic examination with a history of recurrent choking attacks or aspiration symptoms. 2. Children aged from 6 months to 5 years. Exclusion Criteria: 1. Children with any neurological impairment. 2. Children with other congenital anomalies. 3. Children with other causes of respiratory distress
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What it tests

  • PPI
  • vitamin D
  • feeding instruction
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Where

1 site
faculty of Medicine, Minia University
Minya, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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