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โ† Trials
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Diaphragmatic Ultrasonography in Difficult Weaning

RecruitingNAAges 18 Years - anyAllHospital de Clinicas de Porto Alegre
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In plain words

What the trial is, and whether it could suit you

Weaning from mechanical ventilation (MV) is a gradual process that includes several steps until the complete withdrawal of ventilatory support. Difficult weaning is defined as weaning completed only after the first attempt to withdraw the patient from ventilatory support, that is, a patient who failed the first spontaneous breathing trial (SBT). The use of ultrasound (US) to assess diaphragmatic and extradiaphragmatic muscles, such as the parasternal muscles, has been employed to determine diaphragmatic dysfunction and ventilatory effort, contributing to the decision-making process regarding weaning. Among the tools used for bedside monitoring and evaluation of patients are ventilatory variables that indicate an adequate level of ventilatory assistance in spontaneous modes through ventilatory drive, such as P0.1 (occlusion pressure in the first 100 ms) and assessment of ventilatory effor

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults patients receiving invasive mechanical ventilation who are classified as having difficult weaning, defined as failure of the first spontaneous breathing trial. * Richmond Agitation-Sedation Scale (RASS) score between -2 and +1. * Clinical stability, defined as: * No vasopressor support or only low-dose, stable vasopressor therapy. * Absence of significant cardiac arrhythmias or ongoing myocardial ischemia. * Adequate oxygenation (SpOโ‚‚ \>90% or PaOโ‚‚ \>60 mmHg). * Respiratory rate \<35 breaths/min. Exclusion Criteria: * Inability to obtain informed consent. * Pre-existing neuromuscular disease. * Pregnancy. * Inability to perform the ultrasound examination because of chest drains, surgical wounds, or skin lesions at the assessment sites.
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What it tests

  • Diaphragmatic ultrasound
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Where

1 site
Hospital de Clรญnica de Porto Alegre
Porto Alegre, Brazil
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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