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โ† Trials
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Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission

RecruitingNAAges 18 Years - 60 YearsAllPontificia Universidad Catolica de Chile
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In plain words

What the trial is, and whether it could suit you

This study will evaluate whether a 12-week dietary intervention can improve gut health, inflammation, and quality of life in adults with ulcerative colitis in remission. Participants will be randomly assigned to one of three groups: a Mediterranean diet, a Mediterranean diet combined with time-restricted feeding (eating within an 8-hour window each day), or standard dietary advice. The Mediterranean diet emphasizes fruits, vegetables, whole grains, legumes, nuts, olive oil, and fish, while limiting processed foods and red meat. The main outcome will be changes in short-chain fatty acids in stool samples, which are markers of gut health. Additional outcomes include changes in inflammation markers, gastrointestinal symptoms, and quality of life. The results of this study may help identify effective dietary strategies to support patients with ulcerative colitis.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 to 60 years * Diagnosis of ulcerative colitis * Clinical remission for at least 6 months * Fecal calprotectin \< 250 ยตg/g in the last 3 months * Daily eating window โ‰ฅ 11 hours Exclusion Criteria: * Active ulcerative colitis * History of gastrointestinal surgery * Liver or kidney disease * Pregnancy * Eating disorders * Use of supplements (protein, antioxidants, probiotics) * Current restrictive diets (vegetarian, vegan, gluten-free, low-FODMAP) * High levels of physical activity
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What it tests

  • Mediterranean Diet
  • Mediterranean Diet + Time-Restricted Feeding
  • Standard Dietary Advice
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Where

1 site
Pontificia Universidad Catรณlica de Chile
Santiago, Chile
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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