🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Comparison of Efficacy and Safety of Speedboat Device and Needle Knife for Colorectal Endoscopic Submucosal Dissection: a Multicenter Randomized Study

RecruitingNAAges 18 Years - anyAllMahidol University
NCT07754955 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether a new endoscopic device called the Speedboat works as well or better than the standard needle knife for removing large colonic nonpedunculated polyps. The study will also evaluate the safety of the Speedboat device. The main aims of the study are: * To compare the resection speed of colorectal endoscopic submucosal dissection (ESD) using the Speedboat device versus the standard needle knife. * To compare the en bloc resection rate and curative (R0) resection rate between the two techniques. * To evaluate the safety of using the Speedboat device compared with the needle knife in colorectal ESD. What will happen in this study Adults aged 18 years or older who have a large, flat colorectal polyp (greater than 20 mm) that cannot be safely removed with standard snare polypectomy may take part. Participants will be randomly assigned (like

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 or above with large non-pedunculated colorectal polyp size \> 20 mm. in which 1st endoscopist decided that lesion cannot be resected with endoscopic mucosal resection to achieve en bloc resection Exclusion Criteria: 1. Patients who have coagulopathy which is contraindicated for colonoscopy and polypectomy (Prothrombin time \> 3-second ULN, INR \> 1.5, Platelet \< 50,000) 2. The non-pedunculated lesion that was recurrence from the previous polypectomy or ESD 3. Suspected deep submucosal invasion using image-enhanced endoscopy by expert endoscopist 4. Patients who were diagnosed with inflammatory bowel disease 5. Pregnancy or breastfeeding 6. A patient who is unable to provide consent
💊

What it tests

  • Speedboat
  • Needle knife
📍

Where

1 site
Division of Gastroenterology, Departmnt of Medicine, Faculty of Medicine Siriraj Hospital
Bangkok Noi, Thailand
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy